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Keep in mind that Glucophage will not improve the symptoms of type 1 diabetes. After another drug has been added to or removed from your regimen, you should report worsening of any disease symptoms or medication side effects to your doctor. The full effects of levothyroxine may take weeks to months to realize. Effects of metformin on insulin resistance in obese and hyperandrogenic women. Since Glucophage lowers insulin, diabetics should be existing of yourself if you are insulin resistant fasti...